FORMULATION AND EVALUATION OF VITEX NEGUNDO AND ALOEVERA NANOGEL

Nanogel formulations of Vitex negundo and Aloe vera were developed and included in the gel. The results of the present experiment indicate that formulation F7 shows high entrapment of Vitex negundo and Aloevera nanogel. The plot of the time versus concentration revealed that the optimized formulation F7 follows zero order release pattern. A sustained release of the optimized formulation from the nanogel formulation was observed for 12 hours. Nanogel preparation of the optimized formulation F7 was found to be antibacterial, thereby achieving the objectives of the project. Accordingly, medicinal plants that inhibit their growth without harming the host are potentially useful therapeutic agents